9 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Warfarin, Apixaban, Dabigatran ... #Anticoagulation ... DOAC #Management #Table ... #Pharmacology #
Comparison of oral anticoagulant agents (DOACS + Warfarin)

Reference: ENLS 2017 Pharmacotherapy. Neurocritical Care Journal.

#DOAC #Dosing #Oral
Comparison of oral ... #DOAC #Dosing #Oral ... #Anticoagulation ... #Comparison #Table ... #Pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Renal Dosing ... patients 5mg bid Dabigatran ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Rivaroxaban #Dabigatran
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
modified factor Xa • Dabigatran ... concentrate - If antidotes ... Reversal #NOAC #Oral ... anticoagulant #hematology ... #management #pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... management #algorithm #pharmacology ... #medications #table ... decisionaid #cardiology #hematology ... #warfarin #dosing
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
DOACs for easier dosing ... : apixaban and dabigatran ... Transitioning #Anticoagulation ... #Pharmacology # ... Table
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... clearance (calculated using ... per treatment table ... of Therapy • Dabigatran ... Management #Treatment #pharmacology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
-1 Agonist Dosing ... route by using ... drug to remain stable ... been shown non-inferior ... semaglutide #Diabetes #Pharmacology