11 results
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
anticoagulants (DOACs ... ) for VTE treatment ... #DOAC #Anticoagulants ... VTE #Management #Pharmacology ... #Comparison #Table
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... transfusion as needed Antidotes ... concentrate - If antidotes ... hematology #management #pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... #Interactions #Table ... #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... interruption per treatment ... table ... Perioperative #Management #Treatment ... #pharmacology #
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
Bethanechol • Used in treatment ... • Used as an antidote ... • Used as an antidote ... Cholinergic #Agonists #Pharmacology ... #Table #Summary
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS
Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days)
Preferred
IDSA Recommendations ... mucoadhesive buccal tablet ... chew, or crush tablet ... candida #mucosal #IDSA ... infections #HIVAIDS #pharmacology
IDSA 2017 CDiff Guidelines - Table 7. Potential Treatment Agents for Treatment of the Primary Clostridium difficile
IDSA 2017 CDiff ... Guidelines - Table ... Potential Treatment ... Agents for Treatment ... infection Episode #Pharmacology
Potential Treatment Agents for Treatment of the Primary Clostridium difficile infection Episode
Proven efficacy:
 • Vancomycin -
Potential Treatment ... Agents for Treatment ... ClostridiumDifficile #options #treatment ... #management #pharmacology ... #idsa #table
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
IDSA Recommendations ... with ARV (see Table ... Histoplasmosis #IDSA ... #Prevention #Treatment ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
IDSA Recommendations ... prior history of treatment ... Please refer to the table ... Tuberculosis #TB #IDSA ... infections #HIVAIDS #pharmacology