8 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
calcium for K; also binds ... nonspecifically binds ... #medications #pharmacology ... #table #comparison ... #binders
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
; may have ancillary ... ; may have ancillary ... pill burden - May ... #Table #Comparison ... #Pharmacology #
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... absorption of iron that may ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte
 - Causes hyperkalemia?
 - Safe to
Plasma-Lyte - Causes hyperkalemia ... patients with hyperkalemia ... - May be preferable ... #Crystalloids #pharmacology ... #indications #comparison
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... excretion • Saline May ... Normal #Saline #NS #comparison ... #pharmacology #
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Algorithm for Management ... - Consider K+ binders ... bicarbonate - Consider binders ... (may facilitate ... #Algorithm #Management