292 results
diagnosis differential hepatology clinical liver management pocus ultrasound causes pharmacology algorithm hematology pathophysiology radiology table anticoagulation cardiology abscess cirrhosis treatment
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH) UFH: • Advantages: -
Heparin - Unfractionated ... Heparin (UFH) vs ... Low-Molecular-Weight Heparin ... available than aPTT ... #comparison #Unfractionated
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Evaluate an Abnormal APTT ... : Is the PT or APTT ... K Antagonists, Heparin ... Prolonging the PT or APTT ... cause of Prolonged APTT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... unfractionated heparin ... cause e.g. heparin ... thrombin inhibitors, heparin
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
coagulation #coumadin #heparin ... vWF #thrombin #ptt
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT/PTT ... dysfunction (25%) • Hepatic ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... INR < 2.3 - APTT
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
hemoglobin/hemosiderin, Hepatic ... antiglobulin test, PT/aPTT ... hemosiderin • PT/aPTT
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... #Abnormal #PT #aPTT
Restrictive Cardiomyopathy vs Constrictive Pericarditis - Mitral inflow - Tricuspid inflow - Hepatic vein flow -
Tricuspid inflow - Hepatic ... #Pericarditis #comparison
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... elevated in: • Heparin ... thematttsai #PT #PTT
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Warfarin - 100% Hepatic ... Apixaban - 75% Hepatic ... Dabigatran - 20% Hepatic ... Edoxaban - 50% Hepatic ... Rivaroxaban - 65% Hepatic
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