179 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Evaluate an Abnormal APTT ... : Is the PT or APTT ... K Antagonists, Heparin ... Prolonging the PT or APTT ... cause of Prolonged APTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... cause e.g. heparin ... thrombin inhibitors, heparin ... Reduced liver synthesis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... • Reduced liver
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... inhibitor • Liver ... Thromboplastin Time (PTT ... elevated in: • Heparin ... thematttsai #PT #PTT
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (25%) • Hepatic ... DIC • Severe Liver ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... INR < 2.3 - APTT
Hepatic hydatid cyst: water lily sign

Ivan Stankovic, MD, PhD @Ivan_Echocardio

#Hepatic #hydatid #cyst #WaterLily #sign #liver #ultrasound
Hepatic hydatid ... Ivan_Echocardio #Hepatic ... WaterLily #sign #liver ... #ultrasound #abdominal
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
Heparin - Unfractionated ... Heparin (UFH) vs ... Low-Molecular-Weight Heparin ... as compared to heparin ... available than aPTT
"Playboy Bunny" sign, seen w/hepatic congestion due to R heart failure.

Dr. Josie Acuna @jgacuna

#Hepatic #Congestion #Bunny
" sign, seen w/hepatic ... Acuna @jgacuna #Hepatic ... Playboy #Clinical #Liver ... #Ultrasound #POCUS
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
coagulation #coumadin #heparin ... vWF #thrombin #ptt
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
hemoglobin/hemosiderin, Hepatic ... antiglobulin test, PT/aPTT ... hemosiderin • PT/aPTT