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diagnosis differential hematology treatment algorithm coagulation workup bleeding bruising calcium classification dic disseminated elevated evaluation hemophilia hemostasis hodgkins hypertension hypocalcemia
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... PT (INR), Normal ... PTT, Normal PT ... #coagulation #disorders
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... and the PTT suggests
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - ... Algorithm Elevated PTH ... (High or normal ... Diagnosis #Algorithm #causes ... #endocrinology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... Treat primary cause ... INR < 2.3 - APTT ... #treatment #management
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Hypocalcemia - Diagnosis ... and Management ... (phenytoin) • NORMAL ... #Diagnosis #Management ... #endocrinology
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... 2) PTH - Frankly ... BrighamChiefs #Hypercalcemia ... differential #diagnosis #endocrinology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... may be normal in ... mild cases) •
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Ketosis Disorders ... IVF or PO): The pt ... Glucosuria causes ... differential #diagnosis #management ... #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
with electrolyte disorders ... Vasculitis • Endocrinologic ... Hyperthyroidism, Hypercalcemia ... apnea: CPAP, most pts ... Neurologic disorders
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... other neurological disorders ... positive in 2/3 of pts ... limb or joint disorders
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