22 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... procedures - Infection ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... patients if the cause
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
/PTT • Low plasma ... organ damage Clinical ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #treatment #management
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... are caused by members ... HIV/AIDS, CGD) Clinical ... sn lower in SOT pts ... IA #Diagnosis #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... Idiopathic • Infections ... • ↓ WBC • ↓ PLT ... hematology #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Cytopenia +++ (Plt ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Management of Jehovah's Witness patient in ICU 

Clarify which products may be used 
 - Discuss
Management of Jehovah's ... limit to mission-critical ... platelets, INR, PTT ... pro-actively if anemic ... #CriticalCare #Management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... and M panel Management ... DDX - Other causes ... hematology #diagnosis #management
Graves Disease - Autoimmune Hyperthyroidism
Epidemiology: Most common cause of hyperthyroidism, Incidence peaks at 30-50
Diagnosis: 
1 )
Epidemiology: Most common cause ... Clinical Presentation ... • Methimazole/PTU ... Hyperthyroidism #diagnosis #management ... #endocrinology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... and/or stress • Pts ... /other causes • ... Algorithm #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... SLE], AOSD) • Infection ... with leukopenia, anemia ... ↑ PTT • ↑ Fibrin ... Syndrome #Diagnosis #Management