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hematology differential treatment classification syndrome criticalcare infectiousdiseases oncology overview rheumatology shock abscess activation algorithm aplastic arteritis aspergillus autoimmune b12 babesia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... procedures - Infection ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... #Differential #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
/PTT • Low plasma ... organ damage Clinical ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #Coagulation #diagnosis
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Aspergillus (IA) - Diagnosis ... and Management ... are caused by members ... HIV/AIDS, CGD) Clinical ... #Management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... oncology #hematology #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Cytopenia +++ (Plt ... Drugs, Unknown cause ... #management #treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... and M panel Management ... DDX - Other causes ... #management
Graves Disease - Autoimmune Hyperthyroidism Epidemiology: Most common cause of hyperthyroidism, Incidence peaks at 30-50 Diagnosis: 1 )
Epidemiology: Most common cause ... peaks at 30-50 Diagnosis ... Clinical Presentation ... • Methimazole/PTU ... #management #endocrinology
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... and/or stress • Pts ... /other causes • ... IBD #Algorithm #diagnosis ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SLE], AOSD) • Infection ... with leukopenia, anemia ... ↑ PTT • ↑ Fibrin ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Lung Abscess - Clinical ... Leukocytosis, anemia ... #differential #causes
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