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rheumatology treatment dermatology differential syndrome oncology classification photo disease hemeonc infectiousdiseases lupus blood criticalcare druginduced hemophagocytic hlh leukemia lymphohistiocytosis monkeypox
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... procedures - Infection ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
/PTT • Low plasma ... organ damage Clinical ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #management #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #hematology #oncology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
cryoglobulinemia vasculitis - Diagnosis ... , causes and management ... cryoglobulinemia vasculitis Clinical ... Cryoglobulinemic #Diagnosis ... #Management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... , PTT, and fibrinogen ... result in severe anemia ... immune hemolytic anemia ... #Workup #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Clinical Presentation ... • Symptoms of anemia ... anemia • Cold ... disease #hemolytic #anemia ... #hematology #diagnosis
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Aspergillus (IA) - Diagnosis ... and Management ... are caused by members ... HIV/AIDS, CGD) Clinical ... #Management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Cytopenia +++ (Plt ... #management #treatment ... #summary #rheumatology
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