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hematology differential coagulation abnormal disorders treatment thrombocytopenia activation algorithm blanching bruise bruising dic disease disseminated ecchymosis evaluation hematomas hemophilia hemorrhage
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT, Normal PT
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... Prolonging the PT ... to identify the cause ... of Prolonged APTT ... #prolonged #diagnosis
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Time (PT) 1. ... PT and aPTT 1. ... #aPTT #Prolonged ... #Causes #diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
• Prolonged ... 2B) • Normal PT ... INR • Normal aPTT ... (prolonged if very ... VonWillebrand #Disease #Diagnosis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #aPTT #Prolonged ... #Causes #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... normal in mild cases ... ) • PT/INR & von
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
== NORMAL PT ... /NORMAL PTT: • ... prolonged after ... /ABNORMAL PTT: ... discern these causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... epistaxis, gingival bleeding ... : INR/PT, aPTT(liver ... #Differential #Diagnosis
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
IVF or PO): The pt ... ketoacidosis (DKA) - caused ... Glucosuria causes ... #differential #diagnosis ... #management #endocrinology
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