9 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Is a Systemic Disease ... to identify the cause ... of Prolonged APTT ... #prolonged #diagnosis ... mixing #studies #PTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... Early liver disease ... PT and aPTT 1. ... #aPTT #Prolonged ... #Causes #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... /INR: ↑ • PTT: ... • Severe Liver Disease ... INR < 2.3 - APTT
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... screening for disease ... ) • aPTT is prolonged ... mixing study (aPTT ... normal in mild cases
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... prolonged after ... /ABNORMAL PTT: ... discern these causes
Graves Disease - Autoimmune Hyperthyroidism
Epidemiology: Most common cause of hyperthyroidism, Incidence peaks at 30-50
Diagnosis: 
1 )
Graves Disease - ... Epidemiology: Most common cause ... peaks at 30-50 Diagnosis ... • Methimazole/PTU ... #management #endocrinology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
and Management ... infections are caused ... • Severe and prolonged ... vori Infectious Diseases ... #Management #treatment
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
seen in several disease ... IVF or PO): The pt ... Glucosuria causes ... #differential #diagnosis ... #management #endocrinology
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Pheochromocytoma - Diagnosis ... malignant, pediatric cases ... and Signs: 50% pts ... , induction of anesthesia ... Treatment • Operable disease