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diagnosis hematology differential causes disseminated intravascular abnormal prolonged pt activation algorithm bleeding bruising catastrophe checklist criticalcare hemostasis honc icu isth
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
/PTT • Low plasma ... Acral cyanosis • Hemorrhagic ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... causes #treatment #management
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
and/or aPTT Prolonged ... typically prolong aPTT ... and aPTT 1. ... Massive hemorrhage ... (DIC) c.
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
and aPTT If the ... PT and the aPTT ... • Massive hemorrhage ... intravascularcoagulation (DIC ... #aPTT #Prolonged
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... (DIC) Platelet ... , aPTT: • Expected ... consumption of coagulation ... small vessels #DIC
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
prothrombin time (PT ... thromboplastin time (PTT ... decompensated DIC ... Diagnosis #Honc #DIC ... Intravascular #Coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... /NORMAL PTT: Suggests ... ABNORMAL PTT: Prolongation
Postpartum Hemorrhage - Differential Diagnosis and Management Uterine Atony (80%) - Most PPH Will respond to
Postpartum Hemorrhage ... Diagnosis and Management ... epinephrine prn DIC ... /PTT • Treat with ... #Postpartum #Hemorrhage
Management of Jehovah's Witness patient in ICU Clarify which products may be used - Discuss
Management of Jehovah's ... document (e.g. some pts ... - Be aware of coagulation ... platelets, INR, PTT ... #CriticalCare #Management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
dysfunction • Hemorrhagic ... Hypofibrinogenemia • ↑ PT ... ↑ PTT • ↑ Fibrin ... Syndrome #Diagnosis #Management
Figure 2 Modified Physiological Triage Tool (MPTT)-24 algorithm with increased respiratory rate upper threshold (≥24), conscious level
Physiological Triage Tool (MPTT ... external catastrophic haemorrhage ... JamieVassallo #Management
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