12 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PTTProlonged ... PTTProlonged ... PTTProlonged ... PTT, Normal PT ... Causes #Hematology #coagulation
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
PT - Prolonged ... aPTT and Prolonged ... PT - Prolonged ... aPTT Dr. ... #Abnormal #APTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
and/or aPTT Prolonged ... aPTT) 3. ... PT and aPTT 1. ... (DIC) c. ... #aPTT #Prolonged
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... causes #treatment #management
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... aPTT are both prolonged ... intravascularcoagulation (DIC ... #aPTT #Prolonged ... differential #hematology #coagulation
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... (DIC) Platelet ... , aPTT: • Expected ... consumption of coagulation ... small vessels #DIC
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... prolonged after ... ABNORMAL PTT: Prolongation
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
prothrombin time (PT ... thromboplastin time (PTT ... decompensated DIC ... Diagnosis #Honc #DIC ... Intravascular #Coagulation
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... Chronic Management
Paracentesis Anatomy Landmarks

Don't hit the inferior epigastric artery!!! Go 2cm below the umbilicus in the midline
spine Overall coagulation ... abnormal tests of coagulation ... Prolonged PT) because ... Landmarks #anatomy #management