16 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... + Bleeding Treatment ... INR < 2.3 - APTT ... #management #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
and/or aPTT Prolonged ... typically prolong aPTT ... may prolong the aPTT ... and aPTT 1. ... (DIC) c.
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... (DIC) Platelet ... , aPTT: • Expected ... consumption of coagulation ... small vessels #DIC
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
and aPTT If the ... PT and the aPTT ... intravascularcoagulation (DIC ... #aPTT #Prolonged ... differential #hematology #coagulation
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
prothrombin time (PT ... thromboplastin time (PTT ... decompensated DIC ... Diagnosis #Honc #DIC ... Intravascular #Coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... /NORMAL PTT: Suggests ... ABNORMAL PTT: Prolongation
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... Chronic Management ... #treatment #hematology
REBEL Review 71: Treatment of Thyroid Storm 

Propranolol 
Esmolol 
Propylthiouracil (PTU) 
Methimazole 
Saturated Solution of Potassium
REBEL Review 71: Treatment ... Propylthiouracil (PTU ... Hydrocortisone #endocrinology ... hyperthyroidism #table #management ... #treatment #pharmacology
Management of Jehovah's Witness patient in ICU 

Clarify which products may be used 
 - Discuss
Management of Jehovah's ... document (e.g. some pts ... - Be aware of coagulation ... platelets, INR, PTT ... #CriticalCare #Management
Postpartum Hemorrhage - Differential Diagnosis and Management 
Uterine Atony (80%) - Most PPH Will respond to
Diagnosis and Management ... epinephrine prn DIC ... /PTT • Treat with ... unresponsive to usual treatment ... Differential #Diagnosis #Management