12 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... /PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #management #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
and/or aPTT Prolonged ... typically prolong aPTT ... may prolong the aPTT ... and aPTT 1. ... Disseminated intravascular
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
for Disseminated Intravascular ... Coagulation (DIC ... , aPTT: • Expected ... #Disseminated #Intravascular ... #Coagulation #ISTH
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
prothrombin time (PT ... thromboplastin time (PTT ... #Disseminated #Intravascular ... #Coagulation #Labs
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... and the PTT suggests ... , disseminated intravascular
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... Chronic Management ... #treatment #hematology
REBEL Review 71: Treatment of Thyroid Storm 

Propranolol 
Esmolol 
Propylthiouracil (PTU) 
Methimazole 
Saturated Solution of Potassium
REBEL Review 71: Treatment ... Propylthiouracil (PTU ... Hydrocortisone #endocrinology ... hyperthyroidism #table #management ... #treatment #pharmacology
Management of Jehovah's Witness patient in ICU 

Clarify which products may be used 
 - Discuss
Management of Jehovah's ... document (e.g. some pts ... - Be aware of coagulation ... platelets, INR, PTT ... #CriticalCare #Management
Postpartum Hemorrhage - Differential Diagnosis and Management 
Uterine Atony (80%) - Most PPH Will respond to
Diagnosis and Management ... CBC, fibrinogen, PT ... /PTT • Treat with ... unresponsive to usual treatment ... Differential #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... lymphoma (DLBCL, intravascular ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary