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diagnosis hematology differential coagulation treatment algorithm causes disseminated intravascular pt rheumatology abnormal blood comparison diabetes druginduced hyperthyroidism laboratory lupus nephrology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation (DIC ... /PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... causes #treatment #management
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Prothrombin Time (PT ... Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... elevated in: • DIC ... #PTT #Prothrombin
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
and/or aPTT Prolonged ... typically prolong aPTT ... may prolong the aPTT ... and aPTT 1. ... intravascular coagulation (DIC
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... Differential #Diagnosis #Management
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... intravascularcoagulation (DIC ... #aPTT #Prolonged
Fantastic handout on anticoagulation by Dr. Jessie Donato, superstar medical educator and hospitalist at ⁦@ClevelandClinic⁩ ⁦@CCF_IMCHIEFS⁩ #Anticoagulation
#HeparinDrip #gtt ... #Algorithm #PTT ... #Monitoring #Management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... /NORMAL PTT: Suggests ... PTT suggests liver
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation (DIC ... platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... small vessels #DIC
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
prothrombin time (PT ... thromboplastin time (PTT ... decompensated DIC ... Diagnosis #Honc #DIC
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... Chronic Management ... Hemophilia #Diagnosis #Management
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