17 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... - Prolonged aPTT ... - Prolonged aPTT ... Coagulation #Abnormal #APTT ... #Laboratory #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... • Prolonged PTT ... #Diagnosis #Algorithm ... #Causes #Hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... elevated in: • DIC ... #PTT #Prothrombin ... Thromboplastin #laboratory ... #hematology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #treatment #management ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... /aPTT MAHA likely ... /aPTT normal • ... #Algorithm #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
and aPTT If the ... PT and the aPTT ... intravascularcoagulation (DIC ... #aPTT #Prolonged ... #differential #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... typically prolong aPTT ... and aPTT 1. ... intravascular coagulation (DIC ... #differential #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation (DIC ... , aPTT: • Expected ... small vessels #DIC ... Scoring #diagnosis #hematology ... #laboratory
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... /NORMAL PTT: Suggests ... ABNORMAL PTT: Prolongation ... discern these causes ... Differential #Diagnosis #Hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... #treatment #hematology