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diagnosis hematology differential coagulation management abnormal pt algorithm aspergillus bells bleeding brain bruising clinical crypto cryptococcal dic disease disorders disseminated
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
or APTT Artifactually ... or APTT? ... to identify the cause ... of Prolonged APTT ... mixing #studies #PTT
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT, Normal PT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... aPTT) 3. ... the aPTT alone ... PT and aPTT 1. ... #aPTT #Prolonged
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... PT and aPTT If ... aPTT are both prolonged ... Causes include : ... #aPTT #Prolonged
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... /INR: ↑ • PTT: ... Treat primary cause ... INR < 2.3 - APTT
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
bleeding • Prolonged ... 2B) • Normal PT ... INR • Normal aPTT ... (prolonged if very ... factor VIII) Treatment
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... normal in mild cases ... by a hemophilia treatment
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... prolonged after ... discern these causes
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... • Severe and prolonged ... sn lower in SOT pts ... this morphology Treatment ... Diagnosis #Management #treatment
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
↑ AST/ALT • Treatment ... tenderness Treatment ... Methimazole and PTU ... hyperthyroidism #causes ... #differential #endocrinology
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