23 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PTT • Prolonged ... PT (INR), Normal ... PTT, Normal PT ... , Normal PT (INR ... #Diagnosis #Algorithm
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
the PT or APTT ... Prolonging the PT ... to identify the cause ... #diagnosis #hematology ... mixing #studies #PTT
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Tests - Prolonged PT ... - Prolonged aPTT ... and Prolonged PT ... - Prolonged aPTT ... #Hematology #Diagnosis
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... #Management #Algorithm
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... ) ABNORMAL PT ... /NORMAL PTT: Suggests ... PT/ABNORMAL PTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... Prothrombin Time (PT ... #PT #aPTT #Prolonged ... #Causes #diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... • Prolonged bleeding ... PT/INR • Normal ... aPTT (prolonged ... VonWillebrand #Disease #Diagnosis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #PT #aPTT #Prolonged ... #Causes #diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... established disease) • aPTT ... mixing study (aPTT ... mild cases) • ... PT/INR & von Willebrand