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diagnosis hematology differential coagulation abnormal algorithm causes disease disorders treatment activation anatomy bleeding bruising crohns dic disseminated ecmo evaluation extracorporeal
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Evaluate an Abnormal APTT ... Step 1: Is the PT ... Prolonging the PT ... or APTT? ... APTT ISN Education
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PTT • Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT, Normal PT ... PTT, Normal PT
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
PT - Prolonged ... aPTT and Prolonged ... PT - Prolonged ... aPTT Dr. ... Coagulation #Abnormal #APTT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... and/or aPTT Prolonged ... Prothrombin Time (PT ... PT and aPTT 1. ... #aPTT #Prolonged
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #Abnormal #PT ... #aPTT #Prolonged
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal •
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
bleeding • Prolonged ... 2B) • Normal PT ... INR • Normal aPTT ... (prolonged if very
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
== NORMAL PT ... level NORMAL PT ... /ABNORMAL PTT: ... Perform a PTT mixing ... prolonged after
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... mild cases) • PT
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