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diagnosis hematology differential coagulation clinical pocus causes dic intravascular treatment abnormal algorithm fusarium infections infectiousdiseases prolonged activation acutepe bleeding bruising
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... typically prolong PT ... Disseminated intravascular ... #Abnormal #PT
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal •
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #Abnormal #PT ... #aPTT #Prolonged
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Scoring System for Disseminated ... platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... vessels #DIC #Disseminated
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
== NORMAL PT ... /NORMAL PTT: • ... level NORMAL PT ... /ABNORMAL PTT: ... liver failure, disseminated
Chest Pain - Diagnosis and Workup Algorithm History and Exam Acute life-threatening causes: • Acute myocardial infarction •
EKG • Bedside ultrasound ... , LET, lipase, PT ... . aPTT • Serial
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
prothrombin time (PT ... thromboplastin time (PTT ... LaboratoryFindings #Disseminated
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... mild cases) • PT ... Chronic Management
RV Strain in Pulmonary Embolism on POCUS Echocardiogram A patient is brought by EMS intubated and hypotensive.
your next step in management ... echo (assuming pt ... full code, this pt ... Echocardiogram #clinical #ultrasound
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