14 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Fatty Liver of Pregnancy ... (AFLP) Three syndromes ... defects. 1) HELLP (Hemolysis ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia and Pregnancy ... critically ill pregnant ... defects. 1) HELLP (Hemolysis ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
HELLP Syndrome (Hemolysis ... clinical features: Hemolysis ... (AFLP) • Onset ... #hepatology #obstetrics ... diagnosis #icp #HELLP #AFLP
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
(ALT or AST > ALP ... AIH, Wilsons, Pregnancy ... - AFLP, HELLP ... Cholestatic Pattern (ALP ... Algorithm #diagnosis #hepatology
Causes of Growth Discrepancy: Large for Gestational Age - Differential Diagnosis Algorithm
Maternal Factors:
 • Multiparity
 •
over course of pregnancy ... • Perinatal asphyxia ... Hyperbilirubinemia #Large #GestationalAge ... Complications #Pregnancy
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... iMedEducation #AFLP ... #Fatty #Liver #Pregnancy ... #hepatology #obstetrics
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
melanoma, myeloma • Pregnancy ... Gilbert's syndrome • Hemolysis ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... diagnosis #algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... - Increased ALP ... - Drugs - Pregnancy ... #Phosphatase #ALP ... Diagnosis #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
(Alk phos/ULN ALP ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... Gilbert's syndrome • Hemolysis ... #differential #Hepatology