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diagnosis differential potassium workup anemia causes hemolytic management algorithm blood disease glomerular high nephrotic product reactions agglutinin cold glomerulonephritis infections
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... Extravascular Hemolysis ... Anemia #Laboratory #Testing ... workup #diagnosis #hematology ... #hemolysis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... venipuncture • Hemolysis ... edema • Jaundice/Hemolytic ... cell lysis: - Hemolysis ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... venipuncture • Hemolysis ... edema • Jaundice/Hemolytic ... cell lysis: - Hemolysis ... potassium #high #nephrology
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... blockers - MCW Nephrology ... MCW_Nephrology #HyperKalemia
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... • Tumor lysis/hemolysis ... • Type 1 #Hyperkalemia ... Diagnosis #algorithm #nephrology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... Algorithm #workup #hematology ... #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... • Compensated hemolysis ... post infectious setting ... intravascular hemolysis ... #anemia #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
antibodies leading to hemolysis ... Hemolysis on labs ... , fever, minor hemolysis ... Hypocalcemia, Hyperkalemia ... false negatives on testing
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... injury, ischemia, hemolysis ... Pseudohyperkalemia - hemolysis ... #Hyperkalemia ... Treatment #potassium #nephrology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
antibodies leading to hemolysis ... Hemolysis on labs ... , fever, minor hemolysis ... Hypocalcemia, Hyperkalemia ... diagnosis #management #hematology
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