14 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... on Smear • Chronic ... Deficiency • B12/Folate ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Vitamin B12 or Folate ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
- Anemia of chronic ... of chronic kidney ... Vitamin B12 and/or folate ... #diagnosis #differential ... #workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
with elevated Mean ... Volume (MCV) - Differential ... Neutrophils - Low RBC ... Folate • ... RBCs in Rouleaux
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
(RBC = red blood ... reticulocyte count is elevated ... of the initial work-up ... #VitaminB12 #Folate ... #AAFP
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
transform into a RBC ... , Vitamin B12, Folate ... , Intrinsic RBC ... Production #Index #hematology ... #anemia #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... for workup, including ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... • Infections: Chronic
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... schistocytes, nucleated RBCs ... count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Neutropenia, anemia ... Elevated LDH 5. ... Elevated beta 2 ... Leukemia #diagnosis #workup
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
rheumatic fever • Chronic ... = Worry about late ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #