11 results
Evaluation of Patients with Anemia

Microcytic, Normocytic, Macrocytic, Hemolytic (Intravascular and Extravascular)

#Diagnosis #Anemia #Workup #Macrocytic #Microcytic #Normocytic
Microcytic, Normocytic ... , Macrocytic, Hemolytic ... #Workup #Macrocytic ... #Microcytic #Normocytic ... #Differential #
Anemia - Workup and Differential Diagnosis
 - History, Physical Exam, Labs
 - Microcytic
 - Normocytic
 -
Anemia - Workup ... Exam, Labs - Microcytic ... Normocytic - Macrocytic ... - Hemolytic # ... Anemia #Workup #
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Under 80 = microcytic ... 95 (or 100) is macrocytic ... acute blood loss, hemolysis ... #Hematology #Microcytic ... #Macrocytic
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... • Microcytic - ... Lead poisoning • Macrocytic ... key #diagnosis #differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... (sometimes) Macrocytic ... hemolytic anemia ... hemolytic anemia ... #Morphology #differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Framework by MCV Microcytic ... , CKD • Hemolytic ... - Extrinsic: Autoimmune ... Infections Macrocytic
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... • Blood smear: Differential ... #Hemolytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Hypochromic & microcytic ... RBCs, DAT (-) → ... idiopathic, malignancy, autoimmune ... #Anemia #Differential
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... (RBC = red blood ... Hemorrhage or hemolysis ... of the initial work-up ... #Macrocytosis #Macrocytic
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... elliptocytosis, autoimmune ... #Anemia #Differential ... Diagnosis #Algorithm #workup