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diagnosis hematology algorithm hemolytic management morphology antibody bloodcell causes classification gap globulin hodgkins key lymphoma mcv mds microscopy myelodysplasia myelodysplastic
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(sometimes) Macrocytic ... spherocytosis, Autoimmune ... Agglutinate: Cold autoimmune ... #Morphology #differential ... hematology #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... Lead poisoning • Macrocytic ... #Morphology #Atlas ... key #diagnosis #differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... Infections Macrocytic ... MCV #Algorithm #Differential
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... • Blood smear: Differential ... Warm #Antibody #Autoimmune
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential ... Hypochromic & microcytic ... RBCs, DAT (-) → ... idiopathic, malignancy, autoimmune ... #Differential #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... elliptocytosis, autoimmune ... #Differential # ... Diagnosis #Algorithm #workup
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Weight loss • Anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Workup: • Complete ... blood count with differential ... diagnosis #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
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