11 results
diagnosis differential rheumatology management hemolytic joint pain algorithm antibody approach blood bloodcell classification disorders erythematosus extravascular gap globulin hemolysis hodgkins
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(sometimes) Macrocytic ... spherocytosis, Autoimmune ... IgM associated lymphoma ... differential #diagnosis #hematology ... #microscopy #atlas
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... Warm #Antibody #Autoimmune
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... e.g. lupus, CLL, lymphoma ... • Intrinsic RBC ... differential #diagnosis #hematology ... #anemia
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Pseudo Pelger-Huet, Macrocytic ... anemia - ... bcr-able (+) ↑ WBC ... Amy Chung, MD, MSc ... Blood #Disorders #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full ... classification #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
, erythema and WBC ... Autoimmune → Inflammation ... weeks) Can Be Caused ... Differential #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Lyme), reactive arthritis ... Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Arthralgia and Arthritis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
disease • Non-autoimmune ... Malignancy (e.g. hematologic ... deficiencies • Autoimmune ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... (RA, Temporal arteritis ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... Thalassemia, Sickle cell anemia
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