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diagnosis differential algorithm hemolytic management oncology rheumatology antibody arthritis blood bloodcell classification elevatedmcv extravascular gap globulin hemolysis hodgkins intravascular joint
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(sometimes) Macrocytic ... Unstable hemoglobin disorders ... spherocytosis, Autoimmune ... differential #diagnosis #hematology ... #microscopy #atlas
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (BM) ablative disorders ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic ... #Macrocytic
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Neutrophils - Low RBC ... • Small Bowel Disorder ... RBCs in Rouleaux ... #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... Warm #Antibody #Autoimmune
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Pseudo Pelger-Huet, Macrocytic ... anemia - ... bcr-able (+) ↑ WBC ... Amy Chung, MD, MSc ... #hematology #Markers
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... MCV 80-100 fl) & macrocytic ... Pancytopenia is a hematologic ... that involves disorders ... These causes could
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... membrane disorder ... elliptocytosis, autoimmune ... Diagnosis #Algorithm #workup ... #hematology #testing
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... lymphoproliferative disorders ... • Intrinsic RBC ... differential #diagnosis #hematology ... #anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... common cytopenia: Macrocytic ... Workup: • Complete ... Syndromes #diagnosis #hematology
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