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diagnosis hematology differential algorithm hemolytic antibody blood bloodcell disorders key management markers mcv microcytic microscopy nomenclature red rheumatology testing treatment
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... (sometimes) Macrocytic ... spherocytosis, Autoimmune ... #Morphology #differential ... hematology #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... Lead poisoning • Macrocytic ... coagulopathy (DIC) #RBC ... #Morphology #Atlas
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (up to 100) = normocytic ... for degree of anemia ... thecurbsiders podcast #Anemia ... Algorithm #Diagnosis #Workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Framework by MCV Microcytic ... Normocytic ( ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... Infections Macrocytic
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... Warm #Antibody #Autoimmune
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... other reproducible morphologic ... hypertension • Unusual RBC ... elliptocytosis, autoimmune ... Diagnosis #Algorithm #workup
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Disorder - Abnormal morphology ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... bcr-able (+) ↑ WBC ... Amy Chung, MD, MSc
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