7 results
Anemia - Workup and Differential Diagnosis
 - History, Physical Exam, Labs
 - Microcytic
 - Normocytic
 -
Anemia - Workup ... - Normocytic ... - Macrocytic - ... Hemolytic #Anemia ... #Diagnosis #causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Polychromatic Macrocytes ... Bleed • Hemolysis ... Polychromatic Macrocytes ... Deficiency #Normocytic
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... (sometimes) Macrocytic ... or Folate deficiency ... hematology #microscopy #atlas ... #nomenclature
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Normocytic ( ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Spherocytosis, G6PD, PK, HbC ... Megaloblastic: Folate
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (up to 100) = normocytic ... 95 (or 100) is macrocytic ... acute blood loss, hemolysis ... Algorithm #Diagnosis #Workup
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Anemia 1) DIAGNOSE ... AIHA • Anemia ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... (RBC = red blood ... Hemorrhage or hemolysis ... the most likely cause ... recovery also causes