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diagnosis differential hematology algorithm management treatment cardiology clinical dermatology hemolytic oncology syndrome testing approach arthritis classification endocarditis fever fingernails generalized
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia (sometimes ... Sideroblastic anemia ... iron deficiency anemia ... Autoimmune hemolytic anemia ... hematology #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... , Liver diseases ... coagulopathy (DIC) #RBC ... #Morphology #Atlas
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... • Anemia of Chronic ... Disease • Marrow ... Non-lmmune #Anemia ... Diagnosis #Algorithm #Causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... == Decreased RBC ... Hypertriglyceridemia • Uremia ... • Hemolytic anemia ... End-stage renal disease
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Neutrophils - Low RBC ... • Pancreatic Disease ... RBCs in Rouleaux ... • Liver Disease
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... changes), high MCV anemia ... bypass), LFT (liver disease ... #Workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
(RBC = red blood ... the most likely cause ... recovery also causes ... of the initial work-up ... Homocysteine #Algorithm #Workup
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... → Sickle Cell anemia ... Hypochromic & microcytic RBCs ... malignancy, autoimmune disease ... Diagnosis #Algorithm #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Microangiopathic hemolytic anemia ... • Intrinsic RBC ... Extravascular #Causes ... diagnosis #hematology #anemia
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