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hematology differential algorithm oncology classification rheumatology approach arthritis causes disease hemolytic key laboratory leukemia lymphocytic macrocytic management microscopy pathology testing
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... Unstable hemoglobin disorders ... #diagnosis #hematology ... #microscopy #atlas
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - CD7, CD3 Chronic ... - Abnormal morphology ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC
Red Blood Cell Morphology Atlas Size variation, Hemoglobin distribution, Hypochromia, Shape variation, Inclusions, Red
Red Blood Cell Morphology ... Atlas Size variation ... distribution #Diagnosis ... #RBC #Morphology ... #Atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Atlas • Microcytic ... #Morphology #Atlas ... #key #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... on Smear • Chronic ... • Anemia of Chronic ... Membrane Disorder
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... #RedBloodCell #Morphology ... Morphologies #Key #Atlas ... Pathology #Hematology #Diagnosis
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in peripheral blood ... High in acute blood ... (BM) ablative disorders ... #Workup #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... the peripheral blood ... , Intrinsic RBC ... defects (e.g. sickle cell ... #differential #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... #workup #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... other reproducible morphologic ... membrane disorder ... #Algorithm #workup
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