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diagnosis differential algorithm causes hematology management clinical pathophysiology symptoms signs nephrology neurology workup endocrinology treatment physicalexam pharmacology rheumatology cardiology hemolytic
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
of Vitamin B12 Deficiency ... with vitamin B12 deficiency ... • Deficient intrinsic ... parietal cells by autoantibodies ... (pernicious anemia
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... small intestine), autoantibodies ... (pernicious anemia ... wt loss • If anemia ... B12 #Cobalamin #Deficiency
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... B12 or Folate deficiency ... Cell RBC: G6PD deficiency ... elliptocytosis, Severe iron deficiency
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... anemia, Thalassemia ... Thalassemia, Iron-deficiency ... Post-splenectomy, Vitamin E deficiency ... cells - G-6-PD deficiency
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... Algorithm - Iron deficiency ... anemia - Anemia ... inflammation - Anemia ... and/or folate deficiency
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... LDH • Anti-RBC autoantibodies ... Autoimmune #Hemolytic #Anemia
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach to Anemia ... inflammation) • Iron deficiency ... Sideroblastic anemia ... Megaloblastic: Folate deficiency ... , B12 deficiency
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing SUMMARY: - RDW, FEP, serum iron,
Iron Deficiency ... Anemia vs Anemia ... TIBC-specific for iron deficiency ... Bloodman #Iron #Deficiency ... #Anemia #Chronic
Autoimmune Gastritis - Pathophysiology Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
CD4+ T Cells, Autoantibodies ... Pathophysiology #b12 #deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80 fL) • Iron Deficiency ... Poisoning • Anemia ... 100 fL) • B12 Deficiency ... • Folate Deficiency
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