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diagnosis differential anemia causes antibody cytoplasmic macrocytic patterns rheumatology testing workup aplastic approach classification elevatedmcv macrocytosis management mentzerindex microcytic neutropenia
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Neutropenia with Pancytopenia ... Differential Diagnosis Algorithm ... and non-hematologic ... deficiency: • B12 ... deficiencies #Pancytopenia
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is ... a hematologic condition ... hemoglobin of less than 12 ... The etiology of pancytopenia
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Pancytopenia - Differential ... Diagnosis Algorithm ... • 12-13 g/dL, ... • ANC < 1800/ ... #hematology #workup
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Chronic Bleed - Any ... Reticulocytes, MCV ... Deficiency • B12 ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... and Folate Deficiency ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... - Parvovirus B19 ... • Parvovirus B19 ... • Peripheral Pancytopenia ... Anemia #oncology #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... (cell) volume (MCV ... (EPO), iron or B12 ... iron), low EPO, and ... Diagnosis #Workup #Hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... , OJ, PL-7, PL-12 ... Rods/rings: - HCV ... #Antinuclear #Antibody ... differential #diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... , OJ, PL-7, PL-12 ... Rods/rings: • HCV ... #Antinuclear #Antibody ... differential #diagnosis #rheumatology
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