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hematology diagnosis differential classification aplastic cancer disorders elevatedmcv leukemoid leukocytosis macrocytic macrocytosis management mentzerindex morphologic oncology pancytopenia platelet reticulocyte reticulocytes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Diagnosis Algorithm ... Reticulocytes, MCV ... Deficiency • B12 ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... 80-100 fL) • Bleeding ... (>100 fL) • B12 ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Folate deficiency, B12 ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... - MCV) Low MCV ... Megaloblastic: Vitamin B12 ... differential #diagnosis #causes ... #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Approach to Leukocytosis ... B-symptoms, bruising/bleeding ... hepatomegaly • Labs: anemia ... , ↑ MCV, ↑/↓ platelets ... #hematology #WBC
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... anemia (MCV 80- ... These causes could ... distribution width (RDW ... #RDW #Mentzerindex
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... changes), high MCV ... anemia (vegan, ... - Bone marrow evaluation ... #Workup #hematology
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
General Approach ... to Anemia - Differential ... haptoglobin) 3) Use MCV ... guide further evaluation ... #algorithm #reticulocyte
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... - Parvovirus B19 ... • Parvovirus B19 ... #oncology #hematology
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