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hematology differential causes workup macrocytic oncology pancytopenia classification macrocytosis management mcv reticulocyte thrombocytopenia vitaminb12 wbc aafp approach calculation cancer cbc
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Expectation • Rx Algorithm ... @ZhuoerXie #Aplastic ... #Anemia #diagnosis ... #oncology #hematololgy
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
to Anemia - Differential ... Sideroblastic anemia ... anemia, CKD • ... Folate deficiency, B12 ... MatthewHoMD #Anemia
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
- Differential Diagnosis ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... deficiency: • B12 ... #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... • Symptomatic anemia ... megaloblastic anemia ... #Anemia #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • B12 ... Deficiency • Aplastic ... Anemia • Anemia ... Non-lmmune #Anemia
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... Diagnostic Algorithm ... Iron deficiency anemia ... disease - Vitamin B12 ... #hematology #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Megakaryopoiesis • B12 ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... Marrow Failure • Anemia ... (>100 fL) • B12 ... Myelodysplasia #Anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... ecchymoses, mucosal bleeding ... #hematology #diagnosis
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic Anemia ... • 812, Folate ... #Macrocytic #Anemia ... #differential #diagnosis ... #algorithm #hematology
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