11 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Deficiency • MDS ... Hypothyroid • Liver ... • Alcohol • Drugs ... differential #diagnosis #algorithm ... #hematology #workup
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
80-100 fL) • Bleeding ... Renal Disease, Liver ... (>100 fL) • B12 ... Deficiency • Drugs ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Folate deficiency, B12 ... Orotic aciduria, Drugs ... Non-megaloblastic: Liver ... Reticulocytosis, MDS
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
CHA2DS2VASc vs HAS-BLED ... Abnormal renal/liver ... (cirrhosis, bilirubin ... S Stroke 1 B Bleeding ... Elderly (>65) 1 D Drugs
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... synthetic function may ... RBC (hemolysis, bleeding ... differential #diagnosis #algorithm ... #hepatology
Pancreatitis management checklist 
Evaluation to guide etiology & management 
 - RUQ ultrasound 
 - Calcium
checklist Evaluation ... Triglyceride level - Liver ... potentially causative drugs ... markedly elevated bilirubin ... or postpyloric feeding
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... normal, further evaluation ... hemochromatosis #algorithm ... #diagnosis #management ... #hepatology #gastroenterology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
purpura to mucosal bleeding ... ) • Sepsis • Drug-induced ... thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... Syndrome #Diagnosis #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
ecchymoses, mucosal bleeding ... Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... Anemia #oncology #hematology ... #diagnosis #management