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diagnosis differential injury anemia causes hepatitis transaminitis chemistry classification disorders druginduced elevatedmcv hepatocellular idiosyncratic induced interpretation macrocytic macrocytosis management platelet
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis Algorithm ... exposure to HDS, drugs ... Injury #Diagnosis #Algorithm ... #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... 80-100 fL) • Bleeding ... (>100 fL) • B12 ... Deficiency • Drugs ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Folate deficiency, B12 ... Orotic aciduria, Drugs ... Non-megaloblastic: Liver ... #Diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Blood Smear • Drugs ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... gastric bypass), LFT ... (liver disease) ... - Bone marrow evaluation ... Causes #Workup #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... hepatitis serologies, HCV ... RBC (hemolysis, bleeding ... #differential #Hepatology ... transaminitis #LFTs
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
/B/C/D/E, EBV, CMV ... valproate, azoles), Drugs ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... • Iatrogenic: DILI ... RBC (hemolysis, bleeding ... differential #diagnosis #algorithm ... #hepatology
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