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diagnosis hematology algorithm causes oncology aplastic approach atlas bloodcell elevatedmcv macrocytosis microscopy morphologic morphology myelitis myelodysplasia myelodysplastic neurology nomenclature rbc
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Infections Macrocytic ... , B12 deficiency ... Reticulocytosis, MDS ... #Differential #
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... , Folate Deficiency ... #Anemia #differential ... algorithm #hematology #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
- "Microcytic" ... • Iron deficiency ... - "Macrocytic" ... Megaloblastic: Vitamin B12 ... #differential #
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Corpuscular Volume (MCV ... ) - Differential ... • Drugs Oval Macrocytes ... • Dietary Deficiency ... and Folate Deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... (>100 fL) • B12 ... #MCV #Classification ... #Differential #
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes, MCV ... • B12/Folate ... Deficiency • Aplastic ... #Classification
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... Liver Disease, MDS ... RBC #Morphology #differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... hematology #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Nutritional: vitamin B12 ... Workup: • Complete ... blood count with differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Check Vitamin B12 ... • Nutritional Deficiency ... : - Vitamin B12 ... Myelitis #diagnosis #management ... #neurology #differential
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