11 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... Diagnosis Algorithm Low ... (>100 fL) • B12 ... #MCV #Classification
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
) Low MCV - <80fL ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... deficiency • ... #differential #
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes, MCV ... • B12/Folate ... Deficiency • Aplastic ... #Classification
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... ) - Differential ... • Dietary Deficiency ... - Low Serum B12 ... and Folate Deficiency
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... propylthiouracil) - β-lactam ... may result from low ... hematology #diagnosis #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... LV failure - Low ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... #typea #typeb #classification
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
Modalities of RRT ... SLEDD (Sustained low ... efficiency daily ... dialysis): ~12 ... #Therapy #RRT #managment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... blood count with differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... endocrine: Vitamin B12 ... deficiency • ... dystrophies Work ... CPK aldolase, lactate
Renal Replacement Therapy (RRT) Modalities

RRT Modalities in the ICU:
 • IHD (Intermittent HD):  3-5 hr
RRT Modalities ... SLEDD (Sustained low ... efficiency daily ... dialysis): ~12 ... #Therapy #RRT #managment