29 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... • Drugs Oval Macrocytes ... Neutrophils - Low RBC ... RBCs in Rouleaux
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... , Iron deficiency ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... #Morphology #differential
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... (RBC = red blood ... the most likely cause ... B12 deficiency ... deficiency.
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Polychromatic Macrocytes ... • Early Iron Deficiency ... #Differential #
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin ... B12 deficiency, ... morphologic #mcv #differential ... #diagnosis #causes
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Lead poisoning • Macrocytic ... Post-splenectomy, Vitamin ... coagulopathy (DIC) #RBC ... key #diagnosis #differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Spherocytosis, G6PD, PK, HbC ... Infections Macrocytic ... , B12 deficiency ... MCV #Algorithm #Differential
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes • Iron Deficiency ... • B12/Folate ... Deficiency • Aplastic ... Diagnosis #Algorithm #Causes
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
• Thiamine - Nausea ... cardiomyopathy) • Folate - Macrocytic ... anemiaVitamin ... B12 - Macrocytic ... nutrition #table #differential
Causes of Vitamin B12 Deficiency - Cobalamin
Decreased Intake
Pancreas: Insufficiency
Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... Stomach: Pernicious anemia ... #B12 #Deficiency ... #Cobalamin #differential