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diagnosis hematology algorithm classification management oncology aplastic approach crrt decrease elevation false hba1c hgba1c increase laboratory managment mania manic modalities
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... inflammation) • Iron ... , B12 deficiency ... Reticulocytosis, MDS ... #Differential #
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... ) - Differential ... Volume (<80 fL) • Iron ... (>100 fL) • B12
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes, MCV ... Iron, Ferritin, ... B12/Folate Deficiency ... Diagnosis #Algorithm #Causes
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron ... deficiency • ... Megaloblastic: Vitamin B12 ... #differential # ... diagnosis #causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... RBC turnover • Iron ... deficiency • ... Decrease #Diagnosis #DM2 ... #Differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... to repair DNA, as ... , GATA2 deficiency ... , CTLA4 deficiency ... Hypocellular/Hypoplastic MDS
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis • Bipolar Disorder -> Combination of individual, genetic,
deficiency -> Lack ... of B12 as a cofactor ... Incresed Dopamine D2 ... Manic #Secondary #Causes ... #Differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... rings of excess iron ... blood count with differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... swollen, while in MS ... Predictive of MS ... • Infectious causes ... Multiple sclerosis (MS
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
causing severe altered ... Dialyzer is rigid case ... (Sustained low efficiency ... daily dialysis): ~12 ... by Nick Mark MD
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