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diagnosis hematology algorithm classification aplastic approach decrease elevation false hba1c hgba1c increase laboratory management mania manic mds morphologic myelodysplasia myelodysplastic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... ) - Differential ... Volume (<80 fL) • Iron ... (>100 fL) • B12
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes, MCV ... Iron, Ferritin, ... B12/Folate Deficiency ... Diagnosis #Algorithm #Causes
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron ... deficiency • ... Megaloblastic: Vitamin B12 ... #differential # ... diagnosis #causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... RBC turnover • Iron ... deficiency • ... Decrease #Diagnosis #DM2 ... #Differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... to repair DNA, as ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis • Bipolar Disorder -> Combination of individual, genetic,
deficiency -> Lack ... of B12 as a cofactor ... Incresed Dopamine D2 ... Manic #Secondary #Causes ... #Differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... or folic acid deficiency ... rings of excess iron ... blood count with differential ... diagnosis #hematology #oncology
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