17 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Pernicious Anemia ... - Low Serum B12 ... • Pernicious Anemia ... #Macrocytic #Anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm Low ... Poisoning • Anemia ... Marrow Failure • Anemia ... (>100 fL) • B12
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... Approach - MCV) Low ... Megaloblastic: Vitamin B12 ... morphologic #mcv #differential ... #diagnosis #causes
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... Autoimmune - Pernicious anaemia ... #differential #
Causes of Wide Pulse Pressure - Differential Diagnosis
Physiologic:
 • Advanced age-arteriosclerosis (less compliant arteries)
 • Well
- Severe iron deficiency ... anemia (reduced ... viscosity) - anemia ... fistula - Such as ... #cardiology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework
LOW RETIC INDEX - ↓ PRODUCTION
 • Vitamin
Causes of Anemia ... PRODUCTION • Vitamin B12 ... syndrome, Spur cell anemia ... Autoimmune hemolytic anemia ... Kumfer @AnnKumfer #Anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... in Fanconi anemia ... may result from low
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
, Anemia • Prevalence ... Crohn's > UC Anemia ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... /other causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Vitamin C deficiency ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Anemia • Aplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia