24 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Pancytopenia - Differential ... and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... : • B12/folate
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... (>100 fL) • B12 ... #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron deficiency ... disease - Vitamin B12 ... and/or folate deficiency ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Chronic Bleed - Any ... • B12/Folate ... #Classification ... Algorithm #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... • Dietary Deficiency ... and Folate Deficiency ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... • Fanconi’s anemia ... Inflammatory and ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
formerly known as ... crisis • Severe B12 ... deficiency • Mechanical ... macroangiopathic hemolytic anemia ... #diagnosis #hematology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
, Anemia • Prevalence ... Crohn's > UC Anemia ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... report dehydration as
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Thrombocytopenia - As ... thrombopoietin deficiency ... - Anemia - Bone ... leads to chronic anemia ... Laboratory #Diagnosis #Testing
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, as in Fanconi ... anemia, GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... #oncology #hematology