43 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Chronic Bleed - Any ... • B12/Folate ... #Classification ... Algorithm #Causes #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Pancytopenia - Differential ... and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... : • B12/folate
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... (>100 fL) • B12 ... #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Spherocytosis, G6PD, PK, HbC ... , B12 deficiency ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
: Pyridoxine deficiency ... : Vitamin B12 or ... Folate deficiency ... #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Neutrophils - Low RBC ... • Dietary Deficiency ... and Folate Deficiency ... Algorithm #Causes #Hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron deficiency ... disease - Vitamin B12 ... and/or folate deficiency ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... #Differential # ... Algorithm #workup #hematology ... #testing
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... • Fanconi’s anemia ... Inflammatory and ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Iron deficiency ... loss), Vitamin B12 ... , G6PD deficiency ... Production #Index #hematology ... #anemia #differential