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diagnosis hematology causes approach elevatedmcv fatigue ibd macrocytic macrocytosis neutropenia normocytic oncology pancytopenia thrombocytopenia
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Non-hemolytic: ACD, Aplastic ... , B12 deficiency ... #MCV #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes, MCV ... • B12/Folate ... Deficiency • Aplastic ... #Classification
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... Diagnosis Algorithm ... (>100 fL) • B12 ... #MCV #Classification
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Diagnosis Algorithm ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... Nutritional deficiency ... : • B12/folate
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Megakaryopoiesis • B12 ... Deficiency •
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Corpuscular Volume (MCV ... ) - Differential ... Diagnosis Algorithm ... • Dietary Deficiency ... and Folate Deficiency
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Corpuscular Volume (MCV ... ) - Differential ... Diagnosis Algorithm ... • Marrow Aplasia ... • Early Iron Deficiency
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... , GATA2 deficiency ... , CTLA4 deficiency ... hematology #diagnosis #management
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
, Anemia • Prevalence ... Crohn's > UC Anemia ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... #diagnosis #management
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