57 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... (>100 fL) • B12 ... Classification #Differential ... Diagnosis #Algorithm #Causes
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
disease anemia ... Macrocytic RBC: Vitamin B12 ... Cell Agglutinate: Cold ... , Paroxysmal cold ... RBC #Morphology #differential
Causes of Vitamin B12 Deficiency - Cobalamin
Decreased Intake
Pancreas: Insufficiency
Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... : SIBO, Celiac disease ... Stomach: Pernicious anemia ... #differential #
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... • Dietary Deficiency ... and Folate Deficiency ... • Liver Disease
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... gestation • Vitamin B12 ... #differential # ... diagnosis #signs #symptoms
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... Megaloblastic: Vitamin B12 ... Alcohol use, Liver disease ... morphologic #mcv #differential ... #diagnosis #causes
Dizziness - Differential Diagnosis Framework
"Tell me what you mean by dizzy without using the word dizzy."
Vertigo:
Dizziness - Differential ... neuropathy (DM, B12 ... Coordination/Strength: B12 ... Deficiency/Syphilis ... #Diagnosis #neurology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... • B12/Folate ... Deficiency • Aplastic ... of Chronic Disease ... Diagnosis #Algorithm #Causes
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... , coeliac disease ... low #cobalamin #differential
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal Cord ... : Acid maltase deficiency ... #differential # ... diagnosis #neurology