13 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Acute Thiamine (B1 ... ) Deficiency Clinical ... dysfunction and gait ... Encephalopathy #Thiamine #B1 ... #Deficiency #diagnosis
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... • Thiamine B1 ... #differential #diagnosis ... #signs #symptoms
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
thiamine (vitamin B1 ... ataxia (broad-based gait ... #vitaminB1 #B1 # ... Korsakoff #Syndrome #diagnosis ... #comparison #neurology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... & Fe Sucrose > alt ... restricted diet/deficiency ... /other causes • ... #Algorithm #diagnosis
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
Algorithm for the ... serum level for all ... the most likely cause ... deficiency. ... #Diagnosis #Macrocytosis
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Algorithm Celiac ... disease • Iron-deficiency ... anemia unresponsive ... without discernable cause ... Inflammatory (IBD
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... ) - Waddling gait
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... diarrhea related to IBD ... parasthesias, gait
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
valves, COPD, ILD ... , OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS ... #causes #neurology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... Nonhypoxic • Type B1 ... effect - Thiamine deficiency