10 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Diagnosis Algorithm ... • B12/Folate ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... Approach - MCV) ... Megaloblastic: Vitamin B12 ... #differential #diagnosis ... #causes #hematology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #Cobalamin #Deficiency
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... #differential #diagnosis ... #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... #oncology #hematology ... #diagnosis #management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... of injury • Gait ... Causes: 1. ... myelopathy - Vit B12 ... #neurology #differential
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Check Vitamin B12 ... • Nutritional Deficiency ... : - Vitamin B12 ... #management #neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and pernicious anemia ... brain and spinal cord ... Clinical Manifestations ... • Wide based gait ... Management #treatment #neurology
A quick infographic on the importance of sun protection and the various results of sun damage
#wavelengths #causes ... #diagnosis #dermatology ... non-melanoma skin cancer: clinical ... Cold Spring Harb ... series/integrative-approach-to-skin-cancer-and-sun-protection